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. Author manuscript; available in PMC: 2019 Nov 28.
Published in final edited form as: Chem Rev. 2018 Oct 29;118(22):10840–11022. doi: 10.1021/acs.chemrev.8b00074

Figure 89.

Figure 89.

(A) Crystal structure of membranous bovine heart CcO at 1.6 Å resolution (PDB ID: 5B1B), (B) redox cofactors and H+ and e− pathways via the heme-Cu active site, (C) heme types found in HCOs, (D) redox cofactors active in quinol oxidase catalyzed O2-reduction and the distinct proton pumping mechanism from CcOs. (B) Adapted with permission from ref 843. Copyright 2010 National Academy of Sciences. (C) Adapted from ref 535. Copyright 2004 American Chemical Society. (D) Adapted with permission from ref 840. Copyright 2000 Nature America Inc.