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. Author manuscript; available in PMC: 2020 Feb 1.
Published in final edited form as: Biochem Pharmacol. 2018 Dec 12;160:71–79. doi: 10.1016/j.bcp.2018.12.008

Figure 1. Gene structure, transcripts and proteins products of PPP1R1B gene.

Figure 1.

A. Canonical transcripts (three of the many that have been reported) and two documented protein products. Inclusion of exon 1 creates a transcript that produces Dp32. Inclusion of exon 1b or exon 1c creates a transcript that produces tDp. Also shown are experimentally documented transcription factor binding sites on the gene. B. Schematic diagram showing motifs, phosphorylation sites, and epitopes for commercially available antibodies on Dp32 and tDp. The kinases that phosphorylate Dp32 are: T34: protein kinase A; S45: casein kinase II; T75: cyclin dependent kinases 1 and 5; S102: casein kinase II; S137: casein kinase I [71].