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. 2019 Jan 3;10(2):277–288. doi: 10.1111/1759-7714.12947

Figure 2.

Figure 2

Type I collagen, but not Type III or IV, was identified in lung cancer nests. (a) To explore which type of collagen was expressed in the lung cancer nests, we conducted immunohistochemistry on the tumor tissue. Type I collagen expression was found in human lung tumor tissues. (b) We further assessed xenograft tissue sections from mice transplanted with lung cancer cells using antibodies recognizing Type I, III, and IV collagen. Under 200× magnification, Type I collagen was observed in the cancer nest, while the expression of Type III and IV was barely observed.