Table 2.
Univariate and multivariate analysis of overall survival rate and clinicopathological parameters in 258 pairs of primary ESCCs
| Univariate† | Multivariate‡ | ||
|---|---|---|---|
| Factor | P | HR (95% Cl) | P |
| Gender | 0.707 | 1.029 (0.619–1.711) | 0.911 |
| Male | |||
| Female | |||
| Age | 0.366 | 1.009 (0.980–1.039) | 0.543 |
| ≤60 | |||
| >60 | |||
| Tumor invasion§ | 0.031 | 2.619 (0.198–3.803) | 0.851 |
| T1 | |||
| T2 | |||
| T3 | |||
| Lymph node Metastasis | 0.000 | 0.967 (0.367–2.546) | 0.945 |
| N0 | |||
| N1 | |||
| TNM stage | 0.000 | 1.669 (0.622–4.479) | 0.309 |
| Early stage (I–II) | |||
| Advanced Stage (III‐IV) | |||
| Tumor size (cm3)¶,†† | 0.039 | 2.432 (0.747–7.911) | 0.139 |
| ≤ 5 | |||
| > 5 | |||
| Cell differentiation | 0.000 | 1.808 (1.139–2.870) | 0.012 |
| Well (I–II) | |||
| Moderate (III) | |||
| Poor (IV) | |||
| Collagen I | 0.000 | 0.740 (0.566–0.870) | 0.027 |
| Negative | |||
| Positive | |||
†
By Kaplan–Meier.
‡
By Cox proportional‐hazards regression model.
§
Tumor size was measured and obtained by 0.5 × the length × (the width).2
¶
Partial data was not available, thus all statistics were based on informative data.
††
Invasion was defined by results of final pathological analysis. Bold text indicates a statistically significant difference.
CI, confidence interval; ESCC, esophageal squamous cell carcinoma; TNM, tumor node metastasis.