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. 2019 Jan 8;17:136–141. doi: 10.1016/j.csbj.2019.01.002

Table 1.

MDA-9/Syntenin mediated signaling pathways in different cancers.

Cancer name Signaling pathway
Melanomas NF-κB, c-Src/FAK, p38-MAPK, TF-FVIIa, EGFR, VEGF-A/VEGFR-2, and IGFBP2-HIF1a, et al.,
Breast cancer EGFR, Integrin β1, ERK1/2, estrogen receptor(ER), and CDC42/Rho GTPases, et al.,
Glioblastoma multiforme (GBM) FAK-JNK, FAK-AKT, c-Src, p38-MAPK, NF-κB, SPRR1B, MMP2, NOTCH1, C-Myc, STAT3, and Nanog, et al.,
Small cell lung cancer (SCLC) MT1-MMP, MMP2, ras, rho, and PI3K/MAPK, et al.,
Others TGFβ, FAK, AKT, and c-Src, et al.,