Figure 1.

Survival and surgical complications for bevacizumab plus neoadjuvant chemotherapy versus neoadjuvant chemotherapy alone. Bev, bevacizumab; NAC, neoadjuvant chemotherapy; RCT, randomized controlled trial; T, docetaxel; FEC, fluorouracil plus epirubicin plus cyclophosphamide; AC, doxorubicin plus cyclophosphamide; TX, docetaxel plus capecitabine; TG, docetaxel plus gemcitabine; EC, epirubicin plus cyclophosphamide; q3w, every third week; iv, intravenously; DFS, disease-free survival; OS, overall survival; pCR, pathological complete response; HR, hormone receptor * A hazard ratio or risk ratio less than 1 favors the outcome by Bev plus NAC, while a hazard ratio or risk ratio greater than 1 favors the outcome by NAC alone. F, fixed-effect model; R, random-effect model.