Table 2.
Cervical cancer patients' characteristics and clinical features
| Variables | Patients n=413 (%) | Deaths n=156 (%) | MST (months)a | Log- rank P | HR (95%CI) |
|---|---|---|---|---|---|
| Age (years) | |||||
| ≤55 | 198 (47.94) | 77 (38.89) | 45.03 | 0.262 | 1.00 (Ref.) |
| >55 | 215 (52.06) | 79 (36.74) | 52.36 | 0.83 (0.60-1.15) | |
| Age at menarche (years) | |||||
| <15 | 227 (54.96) | 85 (37.44) | 51.20 | 0.884 | 1.00 (Ref.) |
| ≥15 | 186 (45.04) | 71 (38.17) | 52.35 | 1.02 (0.74-1.41) | |
| Age at menopause (years)b | |||||
| <50 | 119 (51.07) | 42 (35.29) | 51.76 | 0.354 | 1.00 (Ref.) |
| ≥50 | 114 (48.93) | 49 (42.86) | 52.63 | 1.17 (0.84-1.62) | |
| Age at first live birth (years)c | |||||
| <25 | 190 (46.68) | 73 (38.02) | 52.53 | 0.840 | 1.00 (Ref.) |
| ≥25 | 217 (53.32) | 81 (37.33) | 45.92 | 1.03 (0.75-1.42) | |
| Smoking status | |||||
| Smoker | 27 (6.54) | 7 (25.93) | 46.17d | 0.053 | 1.00 (Ref.) |
| Nonsmoker | 386 (93.48) | 149 (38.60) | 51.75 | 2.14 (0.99-4.61) | |
| HPV infection | |||||
| Yes | 362 (87.65) | 142 (39.23) | 52.31 | 0.819 | 1.00 (Ref.) |
| No | 51 (12.35) | 14 (27.45) | 43.77 | 1.07 (0.61-1.87) | |
| Menopausal status | |||||
| Premenopausal | 180 (43.58) | 60 (33.33) | 52.03 | 0.023 | 1.00 (Ref.) |
| Postmenopausal | 233 (56.42) | 96 (41.20) | 45.14 | 1.47 (1.06-2.04) | |
| Parity | |||||
| 0-1 | 141 (34.14) | 60 (42.55) | 42.94 | 0.116 | 1.00 (Ref.) |
| ≥2 | 272 (65.86) | 96 (35.29) | 52.38 | 0.77 (0.55-1.07) | |
| Family history of cancer | |||||
| Yes | 278 (67.31) | 107 (38.49) | 52.91 | 0.492 | 1.00 (Ref.) |
| No | 135 (32.69) | 49 (36.30) | 51.90 | 0.89 (0.63-1.25) | |
| Histological types | |||||
| CIN3e | 12 (2.91) | 4 (33.33) | 32.69d | 0.007 | 1.00 (Ref.) |
| Squamous cell carcinoma | 344 (83.29) | 141 (40.99) | 45.93 | 1.29 (0.47-3.53) | |
| Adenocarcinomas | 50 (12.11) | 10 (20.00) | 51.05d | 0.52 (0.16-1.72) | |
| Adenosquamous carcinoma | 7 (1.69) | 1 (14.29) | 41.00d | 0.44 (0.05-3.98) | |
| Stage | |||||
| CIN3e | 4 (0.97) | 3 (75.00) | 56.62 | 0.174 | 1.00 (Ref.) |
| I | 101 (24.46) | 44 (43.56) | 44.31 | 1.32 (0.38-4.55) | |
| II | 238 (57.63) | 87 (36.55) | 52.12 | 1.10 (0.33-3.71) | |
| III | 65 (15.74) | 21 (32.31) | 51.01 | 0.81 (0.22-2.89) | |
| IV | 5 (1.21) | 1 (20.00) | 52.00 | ||
| Chemotherapy | |||||
| Yes | 273 (66.10) | 99 (36.26) | 52.69 | 0.456 | 1.00 (Ref.) |
| No | 140 (33.90) | 57 (40.71) | 44.35 | 1.13 (0.81-1.58) | |
a MST: median survival time; b Information was available in 91/233 (deaths/patients) postmenopausal women; c Information was available in 153/407 (deaths/patients) cases with parity; d Mean survival time was provided when MST could not be calculated; e CIN, cervical intraepithelial neoplasia.