Table 1.
MHC Class II Gene Expression Modified by Antibiotic Treatment
| MHC class II antigen presentation–associated genes | |||
|---|---|---|---|
| Gene | VEH | ABX | P value |
| H2-Aa | 5717.26 ± 849 | 3988.75 ± 987 | 0.037 |
| H2-DMb2 | 317.52 ± 135 | 182.45 ± 57 | 0.057 |
| H2-Eb1 | 1082.71 ± 349 | 703.77 ± 211 | 0.056 |
| H2-Ob | 304.93 ± 103 | 219.61 ± 45 | 0.090 |
| Ciita | 173.74 ± 82 | 104.58 ± 20 | 0.076 |
| Cd74 | 7260.18 ± 2589 | 4401.80 ± 1085 | 0.044 |
| Ctss | 3139.61 ± 405 | 2309.16 ± 287 | 0.015 |
| Ctsc | 1118.08 ± 130 | 873.48 ± 117 | 0.031 |
| Cd86 | 209.11 ± 54 | 121.94 ± 19 | 0.023 |
Gene expression tested by nCounter analysis, represented as total RNA counts. n = 4 per group. Unpaired t-test was used. Data are expressed as means ± SEM. Significant values (P < 0.05) are in bold.
ABX, antibiotic; VEH, vehicle.