Table 1.
List of O‐GlcNAcylated proteins related with proliferation and progression of cancer
| UniProt accession | Gene name | Protein description | log(intensity)a | Cellular compartmentb | Function | Reference |
|---|---|---|---|---|---|---|
| Reported O‐GlcNAcylated proteins | ||||||
| P60709 | ACTB | Actin, beta | 8.33 | Cytoplasm | – | – |
| P16403 | HIST1H1C | Histone cluster 1 H1c | 7.78 | Nucleus | Proliferation | Song et al. (2008) |
| Migration | ||||||
| Invasion | ||||||
| P10412 | HIST1H1E | Histone cluster 1 H1e | 7.74 | Nucleus | Proliferation | Lee et al. (2013) |
| P16401 | HIST1H1B | Histone cluster 1 H1b | 7.69 | Nucleus | Carcinogenesis | Khachaturov et al. (2014) |
| P02545 | LMNA | Lamin A/C | 7.56 | Nucleus | Proliferation | Kong et al. (2012) |
| Migration | ||||||
| Invasion | ||||||
| P06748 | NPM1 | Nucleophosmin (nucleolar phosphoprotein B23 numatrin) | 7.49 | Cytoplasm | Proliferation | Ching et al. (2015) |
| Nucleus | Migration | |||||
| Invasion | ||||||
| P22626 | NRNPA2B1 | Heterogeneous nuclear ribonucleoprotein A2/B1 | 7.32 | Nucleus | Proliferation | Chen et al. (2014) |
| Migration | ||||||
| Invasion | ||||||
| Q09666 | AHNAK | AHNAK nucleoprotein | 7.10 | Nucleus | Proliferation | Sudo et al. (2014) |
| Migration | ||||||
| Invasion | ||||||
| P07355 | ANXA2 | Annexin A2 | 7.07 | Membrane | Proliferation | Chaudhary et al. (2014) and Wang et al. (2015) |
| Cytoplasm | Migration | |||||
| Nucleus | Invasion | |||||
| Unreported O‐GlcNAcylated proteins | ||||||
| P46939 | UTRN | Utrophin | 8.49 | Membrane | Proliferation | Li et al. (2007) |
| Cytoplasm | ||||||
| Q5QNW6 | HIST2H2BF | Histone cluster 2 H2bf | 8.43 | Nucleus | – | – |
| P62805 | HIST1H4A | Histone cluster 2 H4a | 8.16 | Nucleus | Proliferation | Yan‐Fang et al. (2015) |
| B9ZVM9 | TCP10L2 | T‐complex protein 10A homolog 2 | 7.95 | Nucleus | Proliferation | (Shen et al., 2015) |
| Q16695 | HIST3H3 | Histone cluster 3 H3 | 7.50 | Nucleus | Proliferation | (Xu et al., 2014) |
| P08195 | SLC3A2 | Solute carrier family 3 (amino acid transporter heavy chain), member 2 | 7.09 | Membrane | Proliferation | Fei et al. (2014), Santiago‐Gomez et al. (2013) and Yang et al. (2007) |
| Cytoplasm | Migration | |||||
| Nucleus | Invasion | |||||
| Q16819 | MEP1A | Meprin A subunit alpha | 6.96 | Membrane | Migration | Minder et al. (2012) |
| Invasion | ||||||
| P61978 | HNRNPK | Heterogeneous nuclear ribonucleoprotein‐K | 6.81 | Cytoplasm | Proliferation | Chung et al. (2014) and Gao et al. (2013) |
| Nucleus | Migration | |||||
| Invasion | ||||||
| P27824 | CANX | Calnexin | 6.73 | Cytoplasm | Carcinogenesis | Dissemond et al. (2004) |
| Metastasis | ||||||
| Q08170 | SRSF4 | Serine/arginine‐rich splicing factor 4 | 6.26 | Nucleus | Proliferation | Gabriel et al. (2015) |
| Q5T200 | ZC3H13 | Zinc finger CCCH‐type containing 13 | – | – | ||
| Q7Z7G8 | VPS13B | Vacuolar protein sorting 13 homolog B | – | – | ||
a
Log (intensity) of identified OGPs in KKU‐213.
b
According to GeneCards®: The Human Gene Database.