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. 2018 Dec 21;13(2):322–337. doi: 10.1002/1878-0261.12405

Table 1.

Putative target genes regulated by (A) miR‐455‐5p and (B) miR‐455‐3p in PCa cells

(A)
Entrez gene ID Gene symbol Gene name Location No. conserved sites No. poorly conserved sites PC3 miR‐455‐5p transfectant (Log2 ratio)
5738 PTGFRN Prostaglandin F2 receptor inhibitor 1p13.1 1 0 −2.78
137075 CLDN23 Claudin 23 8p23.1 0 1 −2.73
11031 RAB31 RAB31, member RAS oncogene family 18p11.22 0 3 −2.63
66008 TRAK2 Trafficking protein, kinesin binding 2 2q33.1 1 1 −2.63
7084 TK2 Thymidine kinase 2, mitochondrial 16q21 0 2 −2.56
10959 TMED2 Transmembrane emp24 domain trafficking protein 2 12q24.31 1 1 −2.45
3964 LGALS8 Lectin, galactoside‐binding, soluble, 8 1q43 0 1 −2.44
4201 MEA1 Male‐enhanced antigen 1 6p21.1 0 1 −2.41
9563 H6PD Hexose‐6‐phosphate dehydrogenase (glucose 1‐dehydrogenase) 1p36.22 0 1 −2.38
141 ADPRH ADP‐ribosylarginine hydrolase 3q13.33 0 2 −2.37
2820 GPD2 Glycerol‐3‐phosphate dehydrogenase 2 (mitochondrial) 2q24.1 0 2 −2.33
8544 PIR Pirin (iron‐binding nuclear protein) Xp22.2 0 1 −2.29
29943 PADI1 Peptidyl arginine deiminase, type I 1p36.13 0 1 −2.29
7804 LRP8 Low‐density lipoprotein receptor‐related protein 8, apolipoprotein e receptor 1p32.3 0 2 −2.28
314 AOC2 Amine oxidase, copper containing 2 (retina‐specific) 17q21.31 0 1 −2.25
4038 LRP4 Low‐density lipoprotein receptor‐related protein 4 11p11.2 0 1 −2.17
64506 CPEB1 Cytoplasmic polyadenylation element binding protein 1 15q25.2 1 0 −2.15
8000 PSCA Prostate stem cell antigen 8q24.3 0 1 −2.14
8895 CPNE3 Copine III 8q21.3 0 1 −2.11
8228 PNPLA4 Patatin‐like phospholipase domain containing 4 Xp22.31 0 1 −2.08
127343 DMBX1 Diencephalon/mesencephalon homeobox 1 1p33 0 2 −2.05
54749 EPDR1 Ependymin related 1 7p14.1 0 2 −1.98
3992 FADS1 Fatty acid desaturase 1 11q12.2 0 2 −1.97
659 BMPR2 Bone morphogenetic protein receptor, type II (serine/threonine kinase) 2q33.2 0 2 −1.96
1047 CLGN Calmegin 4q31.1 0 1 −1.94
100128927 ZBTB42 Zinc finger and BTB domain containing 42 14q32.33 0 2 −1.94
10584 COLEC10 Collectin subfamily member 10 (C‐type lectin) 8q24.12 0 2 −1.90
143903 LAYN Layilin 11q23.1 1 1 −1.87
22873 DZIP1 DAZ interacting zinc finger protein 1 13q32.1 0 1 −1.84
79718 TBL1XR1 Transducin (beta)‐like 1 X‐linked receptor 1 3q26.32 1 0 −1.84
56180 MOSPD1 Motile sperm domain containing 1 Xq26.3 0 1 −1.84
3486 IGFBP3 Insulin‐like growth factor binding protein 3 7p12.3 0 1 −1.82
84327 ZBED3 Zinc finger, BED‐type containing 3 5q13.3 0 2 −1.80
203447 NRK Nik‐related kinase Xq22.3 0 1 −1.78
1238 ACKR2 Atypical chemokine receptor 2 3p22.1 0 1 −1.77
9194 SLC16A7 Solute carrier family 16 (monocarboxylate transporter), member 7 12q14.1 0 3 −1.76
128989 TANGO2 Transport and golgi organization 2 homolog (Drosophila) 22q11.21 0 1 −1.74
9870 AREL1 Apoptosis‐resistant E3 ubiquitin protein ligase 1 14q24.3 0 1 −1.72
5500 PPP1CB Protein phosphatase 1, catalytic subunit, beta isozyme 2p23.2 0 1 −1.71
6444 SGCD Sarcoglycan, delta (35 kDa dystrophin‐associated glycoprotein) 5q33.3 0 1 −1.70
4942 OAT Ornithine aminotransferase 10q26.13 0 1 −1.66
116071 BATF2 Basic leucine zipper transcription factor, ATF‐like 2 11q13.1 0 1 −1.65
286077 FAM83H Family with sequence similarity 83, member H 8q24.3 0 1 −1.64
414149 ACBD7 Acyl‐CoA binding domain containing 7 10p13 0 2 −1.64
100132386 KRTAP4‐9 Keratin associated protein 4‐9 17q21.2 0 2 −1.63
55163 PNPO Pyridoxamine 5′‐phosphate oxidase 17q21.32 0 1 −1.63
23414 ZFPM2 Zinc finger protein, FOG family member 2 8q22.3 1 0 −1.63
26049 FAM169A Family with sequence similarity 169, member A 5q13.3 0 2 −1.63
83394 PITPNM3 PITPNM family member 3 17p13.2 0 1 −1.63
132228 LSMEM2 Leucine‐rich single‐pass membrane protein 2 3p21.31 0 1 −1.61
8428 STK24 Serine/threonine kinase 24 13q32.2 1 0 −1.60
4352 MPL Myeloproliferative leukemia virus oncogene 1p34.2 0 1 −1.60
1901 S1PR1 Sphingosine‐1‐phosphate receptor 1 1p21.2 1 1 −1.60
9258 MFHAS1 Malignant fibrous histiocytoma amplified sequence 1 8p23.1 1 0 −1.59
9779 TBC1D5 TBC1 domain family, member 5 3p24.3 0 1 −1.58
57722 IGDCC4 Immunoglobulin superfamily, DCC subclass, member 4 15q22.31 0 1 −1.57
144110 TMEM86A Transmembrane protein 86A 11p15.1 1 1 −1.57
2782 GNB1 Guanine nucleotide binding protein (G protein), beta polypeptide 1 1p36.33 0 1 −1.56
255027 MPV17L MPV17 mitochondrial membrane protein‐like 16p13.11 0 1 −1.56
81031 SLC2A10 Solute carrier family 2 (facilitated glucose transporter), member 10 20q13.12 0 1 −1.55
9214 FAIM3 Fas apoptotic inhibitory molecule 3 1q32.1 0 1 −1.55
153339 TMEM167A Transmembrane protein 167A 5q14.2 1 0 −1.54
8498 RANBP3 RAN binding protein 3 19p13.3 1 0 −1.54
11337 GABARAP GABA(A) receptor‐associated protein 17p13.1 0 1 −1.54
83445 GSG1 Germ cell associated 1 12p13.1 0 2 −1.53
142940 TRUB1 TruB pseudouridine (psi) synthase family member 1 10q25.3 0 1 −1.53
10423 CDIPT CDP‐diacylglycerol‐inositol 3‐phosphatidyltransferase 16p11.2 0 1 −1.53
4155 MBP Myelin basic protein 18q23 0 1 −1.52
374900 ZNF568 Zinc finger protein 568 19q13.12 0 1 −1.52
9658 ZNF516 Zinc finger protein 516 18q23 1 1 −1.51
(B)
Entrez gene ID Gene symbol Gene name Location No. conserved sites No. poorly conserved sites PC3 miR‐455‐3p transfectant (Log2 ratio)
9887 SMG7 SMG7 nonsense‐mediated mRNA decay factor 1q25.3 0 1 −2.24
81033 KCNH6 Potassium voltage‐gated channel, subfamily H (eag‐related), member 6 17q23.3 0 1 −2.08
8778 SIGLEC5 Sialic acid binding Ig‐like lectin 5 19q13.41 0 1 −2.02
92558 CCDC64 Coiled‐coil domain containing 64 12q24.23 0 1 −1.88
23201 FAM168A Family with sequence similarity 168, member A 11q13.4 0 2 −1.86
50615 IL21R Interleukin‐21 receptor 16p12.1 0 1 −1.81
56479 KCNQ5 Potassium voltage‐gated channel, KQT‐like subfamily, member 5 6q13 0 3 −1.81
7099 TLR4 Toll‐like receptor 4 9q33.1 0 2 −1.77
85441 HELZ2 Helicase with zinc finger 2, transcriptional coactivator 20q13.33 0 1 −1.76
339327 ZNF546 Zinc finger protein 546 19q13.2 0 1 −1.76
79663 HSPBAP1 HSPB (heat shock 27 kDa) associated protein 1 3q21.1 1 0 −1.75
81027 TUBB1 Tubulin, beta 1 class VI 20q13.32 0 1 −1.71
23046 KIF21B Kinesin family member 21B 1q32.1 0 2 −1.71
1236 CCR7 Chemokine (C‐C motif) receptor 7 17q21.2 0 1 −1.66
1002 CDH4 Cadherin 4, type 1, R‐cadherin (retinal) 20q13.33 0 1 −1.61
1238 ACKR2 Atypical chemokine receptor 2 3p22.1 0 1 −1.59
150372 NFAM1 NFAT activating protein with ITAM motif 1 22q13.2 0 3 −1.53
283078 MKX Mohawk homeobox 10p12.1 0 1 −1.51