FGFR3 mutation and RB1 mutation in different TMITs of bladder tumors. (a) Scatter plot for the distribution of FGFR3 mutation between different TMITs. (b) Labelling points for the comparation of amino acid changes by FGFR3 mutation in TMIT I and TMIT II bladder tumors. (c) Scatter plot for the distribution of RB1 mutation between different TMITs. (d) Labelling points for the comparation of amino acid changes by RB1 mutation in TMIT I and TMIT II bladder tumors. TMIT, tumor microenvironment immune type; wt, wide type; mut, mutation; Ig, Immunoglobulin domain; I-set, Immunoglobulin I-set domain; Pkinase_Tyr, Protein tyrosine kinase.