Table 5.
Logistic regression analysis for predicting tumor microenvironment immune type I according to clinical characteristics
| Univariate analysis | Multivariate analysis | |||||
|---|---|---|---|---|---|---|
| OR (95% CI) | P value | OR (95% CI) | P value | |||
| Age | 1.003(0.984~1.022) | 0.760 | / | / | ||
| Gender | 0.821(0.522~1.291) | 0.393 | / | / | ||
| Number of mutations | ≥Median | 1.979(1.314~2.981) | 0.001 | 1.055 (0.548~2.031) | 0.874 | |
| Cytolytic activity | ≥Median | 33.455(17.416~64.264) | 5.73E-26 | 5.599 (2.335~13.422) | 1.13E-04 | |
| PD-L1 amplification | Yes | 4.179(2.555~6.836) | 1.23E-08 | 11.454 (4.288~30.599) | 1.00E-06 | |
| IFN-γ mRNA expression TIGIT mRNA expression | ≥Median | 35.520(19.100~73.704) | 6.79E-26 | 10.806 (4.453~26.224) | 1.42E-07 | |
| ≥Median | 27.143(14.661~50.251) | 8.20E-26 | 6.296 (2.702~14.671) | 2.00E-05 | ||
OR, odds ratio; CI, confidence interval.