Table 1.
Clinicopathologic characteristics according to FOXM1 expression
| Variables | Overall | FOXM1 expression | ||
|---|---|---|---|---|
| Low | High | p-value | ||
| Age (years)* | 68.8, 70.0 (± 7.2) | 69.7 (± 7.3) | 68.1 (± 7.0) | 0.242 |
| BMI (kg/m2)* | 23.3, 22.9 (± 2.6) | 23.3 (± 2.6) | 23.3 (± 2.7) | 0.922 |
| Preoperative PSA (ng/mL)* | 11.0, 6.8 (± 16.7) | 7.5 (± 8.2) | 14.8 (± 22.2) | 0.023 |
| Prostate volume (mL)*† | 43.7, 35.0 (± 24.1) | 53.3 (± 26.9) | 31.9 (± 12.9) | <0.001 |
| Pathologic T stage (%) | 0.047 | |||
| 2 | 58 (70.7) | 26 (86.7) | 32 (61.5) | |
| 3a | 10 (12.2) | 1 (3.3) | 9 (17.3) | |
| 3b | 14 (17.1) | 3 (10.0) | 11 (21.2) | |
| Pathologic N stage (%) | 0.004 | |||
| X | 55 (67.1) | 26 (86.7) | 29 (55.8) | |
| 0 | 27 (32.9) | 4 (13.3) | 23 (44.2) | |
| 1 | 0 (0) | 0 (0) | 0 (0) | |
| Pathologic Gleason score (%) | <0.001 | |||
| ≤ 6 | 17 (20.7) | 15 (50.0) | 2 (3.8) | |
| 7 (3+4) | 30 (36.6) | 7 (23.3) | 23 (44.2) | |
| 7 (4+3) | 22 (26.8) | 6 (20.0) | 16 (30.8) | |
| ≥ 8 | 13 (15.9) | 2 (6.7) | 11 (21.2) | |
| Positive surgical margin (%) | 31 (37.8) | 9 (30.0) | 22 (42.3) | 0.268 |
| Lymphovascular invasion (%) | 3 (3.7) | 1 (3.3) | 2 (3.8) | 0.905 |
| Perineural invasion (%) | 55 (67.1) | 17 (56.7) | 38 (73.1) | 0.128 |
* Values are expressed as mean, median (±SD).
† Prostate volume was measured by transrectal ultrasonography.
BMI, body mass index; PSA, prostate-specific antigen; FOXM1, Forkhead box M1