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. 2019 Jan 7;13(2):376–391. doi: 10.1002/1878-0261.12410

Figure 2.

Figure 2

Regression models predictive for IHC‐based observed expression of Ki67 (A), ER (B), and tumor grade (C). Expression levels of chemokines CCL13, CXCL17, CXCL9, CXCL5, CXCL8 (IL‐8), and CCL23 contribute together with other proteins to key properties of BC. ‘Observed’ denotes the IHC values (Ki67 or ER IHC staining positivity) for each of the samples on a continuous scale (0–10, 0–100, or 0–3 for Ki67, ER, and tumor grade, respectively, X‐axis). ‘Predicted’ is the quantitative score assigned by the algorithm along the same continuous range (Y‐axis). Member proteins in the signature are described in the text.