Table 4.
Peak anti-PA IgG |
Peak ED50 |
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---|---|---|---|---|---|
754-IM |
754-IM |
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Time point (Months) | NHP N | Human N | % Survival (95% CI) | Human N | % Survival (95% CI) |
7 | 137 | 636 | 83.4 (76.2–89.2) | 289 | 79.3 (72.1–85.7) |
The human and NHP studies have been described in detail previously [9,10]. Predicted % survival in human cohorts based on the NHP peak anti-PA IgG model. The 7-IM, 5-IM and 4-IM groups were combined as 754-IM since they received the same treatment at this month 7 time point. Confidence intervals (95% CI) are in parentheses.