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. 2019 Jan 20;2019:8274903. doi: 10.1155/2019/8274903

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Copyright © 2019 Diane I. Bitzinger et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

Illustration of the mean survival times of the animals in the four groups. Immediately after CLP induction, the rats were treated with either physostigmine, neostigmine, or saline four times over 24 h. While physostigmine-treated animals survived significantly longer than the control rats receiving the saline, the mean survival time of neostigmine-treated animals was not significantly longer (mean survival time in hours, control (n = 18): 17.5 ± 2.6 vs. physostigmine (n = 14): 20.5 ± 2.3 (^§p < 0.05); control vs. neostigmine (n = 14): 18.3 ± 2.9 (p = n.s.)). Box plots in panels represent medians with 25% and 75% percentiles; error bars are minimum and maximum values, Kruskal-Wallis test followed by Bonferroni's pairwise comparison test.