Table 1.
Constituent compounds in A. africana extract and associated activities that enhance wound healing.
S/No | Class of compound | Phytochemical compounds | Compound structure | Activities that enhances wound healing | Reference |
---|---|---|---|---|---|
a | Monoterpenes | carene |
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(i) Anti-inflammatory (ii) Antimicrobial |
[19–26] |
| |||||
b | Phytocannabinoids | Caryophyllene |
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(i) Antimicrobial (ii) Anti-inflammatory |
[19, 27–35] |
| |||||
c | Sesquiterpenes | Germacrene D |
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(i) Anti-inflammatory (ii) Anti-microbial and (iii) Anti-oxidant |
[36–44] |
| |||||
d | Terpene | α-pinene |
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(i) Anti-microbial (ii) Anti-inflammatory (iii) Increases basic fibroblast growth factor (BFGF) (iv) Increases platelet derived growth factor |
[45–53] |
| |||||
e | Acyclic diterpene alcohol | Phytol |
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(i) Induces oxidative stress on microbial organisms (ii) Reduces interleukin-1β and tumor necrosis factor-α levels |
[4, 20, 54–60] |
| |||||
f | Fatty acid | Linolenic acid |
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(i) Anti-microbial (ii) Down regulate inflammatory inducible nitric oxide synthase (iNOS). |
[20, 61–63] |