Table 4.
Area under curve (AUC) comparison of receiver operator characteristic (ROC) curves for the association with renal failure or ISKDC classification.
| Factors | ECr a | CRF b | ISKDC III-IV | Crescents | ||||
|---|---|---|---|---|---|---|---|---|
| AUC | 95% C.I. | AUC | 95% C.I. | AUC | 95% C.I. | AUC | 95% C.I. | |
| Glomerular M1 count | 0.724 | 0.578 to 0.842 | 0.656 | 0.507 to 0.786 | 0.611 | 0.461 to 0.747 | 0.637 | 0.484 to 0.772 |
| Glomerular M2 count | 0.617 | 0.467 to 0.752 | 0.610 | 0.460 to 0.746 | 0.804 | 0.666 to 0.904 | 0.833 | 0.696 to 0.926 |
| Tubulointerstitial M1 count | 0.769 | 0.627 to 0.878 | 0.700 | 0.552 to 0.822 | 0.602 | 0.452 to 0.739 | 0.696 | 0.545 to 0.822 |
| Tubulointerstitial M2 count | 0.818 | 0.682 to 0.914 | 0.872 | 0.745 to 0.950 | 0.778 | 0.637 to 0.884 | 0.830 | 0.692 to 0.923 |
| ISKDC classification | 0.711 | 0.562 to 0.833 | 0.716 | 0.568 to 0.837 | ||||
aDefinition of elevation of creatinine (ECr) is the status of high creatinine ≥1.0 mg/dl.
bDefinition of chronic renal failure (CRF) is the status of low GFR, which is below 60 ml/min/1.73 m2 for more than 3 months.
ISKDC, International Study of Kidney Disease in Children.