Table 3.
Cut-off values and univariate analysis of PET metabolic parameters for prediction of suboptimal cytoreduction
| Median (range) | Cut-off value | AUC | P value | OR | 95% CI | P value | Predictive score | |
|---|---|---|---|---|---|---|---|---|
| PET 0 | 3.5 (0.0–16.0) | > 2.2 | 0.670 | 0.0277 | 5.250 | 1.41–19.59 | 0.0136 | 5 |
| PET 1 | 4.0 (0.0–14.3) | > 7.9 | 0.657 | 0.0563 | 4.148 | 1.13–15.19 | 0.0317 | 4 |
| PET 2 | 4.5 (0.0–23.0) | > 5.3 | 0.529 | 0.7387 | 0.440 | 0.12–1.63 | 0.2196 | |
| PET 3 | 3.8 (0.0–18.2) | > 0 | 0.652 | 0.0546 | 5.921 | 1.17–30.02 | 0.0318 | 6 |
| PET 4 | 2.9 (0.0–19.0) | > 1.8 | 0.593 | 0.2599 | 2.889 | 0.78–10.68 | 0.1118 | |
| PET 5 | 4.9 (0.0–18.0) | > 4.3 | 0.500 | 1.000 | 0.553 | 0.17–1.80 | 0.3244 | |
| PET 6 | 10.0 (0.0–24.2) | > 6.7 | 0.510 | 0.9097 | 0.393 | 0.10–1.48 | 0.1683 | |
| PET 7 | 6.1 (0.0–13.2) | > 4.5 | 0.506 | 0.9450 | 0.425 | 0.13–1.40 | 0.1599 | |
| PET 8 | 5.7 (0.0–16.8) | > 6 | 0.631 | 0.1224 | 1.118 | 0.97–1.29 | 0.1180 | |
| WB1SUVmax | 46.4 (7.4–134.0) | > 68.8 | 0.621 | 0.1644 | 3.429 | 0.97–12.14 | 0.0561 | |
| WB2SUVmax | 53.3 (7.4–153.0) | > 76.2 | 0.621 | 0.1957 | 4.148 | 1.13–15.19 | 0.0317 | 4 |
| PCI | 22.0 (7.0–32.0) | > 10 | 0.562 | 0.4448 | 5.760 | 0.66–49.91 | 0.1120 | |
| Age | 58.0 (37–74) | ≥ 60 | 0.500 | 1.000 | 1.000 | 0.30–3.26 | 1.0000 | |
| Ascites | NA | > 500 | 0.515 | 0.8173 | 0.842 | 0.21–3.40 | 0.8107 | |
| Ca 125 | 573.7 (38–6000) | > 1881 | 0.568 | 0.4595 | 2.133 | 0.62–7.39 | 0.2221 | |
| ECOG PS | NA | ≥2 | 0.618 | 0.0746 | 4.091 | 0.97–17.29 | 0.0520 | 4 |
| Stage | NA | IV | 0.603 | 0.1464 | 2.70 | 0.75–9.66 | 0.1265 |
PET Positron emission tomography, WB1SUVmax Whole-body 1 standardized uptake value, WB2SUVmax Whole-body 2 standardized uptake value, PCI Peritoneal cancer index, ECOG PS Eastern cooperative oncology group performance status, NA Not available, AUC Area under the curve, OR Odds ratio, 95% CI 95% confidence interval