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. 2019 Feb 4;18:12. doi: 10.1186/s12938-019-0631-8

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© The Author(s) 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — The profiles of the GM CBF estimation through the center of the hypo- and hyper-perfusion region in the slice shown in Fig. 1. From top to bottom: different levels of Gaussian noise, with a standard deviation of 5, 10 and 15, respectively