Table 2.
Baseline bone mineral density, measured by DEXA and DXR, by anti-CCP status and gender
| All patients | Women | Men | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Anti-CCP | p value | Anti-CCP | p value | Anti-CCP | p value | ||||
| Positive | Negative | Positive | Negative | Positive | Negative | ||||
| DEXA | |||||||||
| Lumbar spine | |||||||||
| z-score, mean (SD) | − 0.63 (1.25) |
− 0.46 (1.39) |
0.14 | − 0.60 (1.17) |
− 0.53 (1.25) |
0.65 | − 0.70 (1.38) |
− 0.31 (1.62) |
0.09 |
| Osteopenia, % | 38 | 36 | 0.54 | 35 | 35 | 0.99 | 44 | 36 | 0.34 |
| Femoral neck | |||||||||
| z-score, mean (SD) | 0.05 (1.24) |
0.03 (0.96) |
0.85 | 0.17 (1.29) |
− 0.11 (0.88) |
0.07 | − 0.14 (1.13) |
0.31 (1.06) |
0.025 |
| Osteopenia, % | 18 | 9 | 0.016 | 14 | 9 | 0.30 | 25 | 8 | 0.017 |
| Femoral Ward | |||||||||
| z-score, mean (SD) | − 0.07 (1.14) |
0.20 (1.16) |
0.028 | 0.00 (1.14) |
0.11 (1.10) |
0.46 | − 0.19 (1.14) |
0.38 (1.25) |
0.009 |
| Osteopenia, % | 21 | 9 | 0.003 | 19 | 10 | 0.70 | 23 | 6 | 0.011 |
| Femoral trochanter | |||||||||
| z-score, mean (SD) | 0.12 (1.18) |
0.18 (1.04) |
0.64 | 0.25 (1.18) |
0.05 (0.97) |
0.19 | − 0.10 (1.17) |
0.43 (1.14) |
0.016 |
| Osteopenia, % | 18 | 14 | 0.29 | 15 | 17 | 0.66 | 23 | 6 | 0.018 |
| DXR, metacarpal | |||||||||
| z-score, mean (SD) | − 0.10 (1.09) | − 0.03 (1.13) |
0.52 | − 0.24 (1.15) |
− 0.23 (1.12) |
0.74 | 0.11 (0.96) |
0.44 (1.09) |
0.047 |
| Osteopenia, % | 22 | 20 | 0.65 | 26 | 26 | 1.00 | 15 | 8 | 0.30 |
p values denote differences between groups, and italicized values are significant. Anti-CCP positivity titer > 25 IU/ml
DEXA dual-energy X-ray absorptiometry, assessed in 557 patients, DXR digital X-ray radiogrammetry, assessed in 391 patients