Table 3.
Baseline bone mineral density measured by DEXA and DXR, by groups with anti-CCP > 500 IU/ml and anti-CCP negative
| All patients | Women | Men | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Anti-CCP | p value | Anti-CCP | p value | Anti-CCP | p value | ||||
| > 500 IU/ml | Negative | > 500 IU/ml | Negative | > 500 IU/ml | Negative | ||||
| n = 180 | n = 277 | n = 103 | n = 183 | n = 77 | n = 94 | ||||
| DEXA | |||||||||
| Lumbar spine | |||||||||
| z-score, mean (SD) | − 0.57 (1.22) |
− 0.48 (1.36) |
0.53 | − 0.53 (1.19) |
− 0.53 (1.25) |
0.97 | − 0.63 (1.27) |
− 0.37 (1.55) |
0.32 |
| Osteopenia, % | 33 | 36 | 0.56 | 31 | 36 | 0.52 | 35 | 37 | 0.85 |
| Femoral neck | |||||||||
| z-score, mean (SD) | − 0.10 (1.10) |
0.02 (0.96) |
0.32 | − 0.04 (1.18) |
− 0.10 (0.89) |
0.69 | − 0.19 (0.99) |
0.28 (1.05) |
0.027 |
| Osteopenia, % | 23 | 9 | 0.002 | 22 | 9 | 0.028 | 24 | 8 | 0.036 |
| Femoral Ward | |||||||||
| z-score, mean (SD) | − 0.19 (1.12) |
0.18 (1.16) |
0.01 | − 0.19 (1.23) |
0.10 (1.10) |
0.13 | − 0.20 (0.96) |
0.35 (1.25) |
0.020 |
| Osteopenia, % | 22 | 9 | 0.004 | 23 | 10 | 0.035 | 20 | 6 | 0.043 |
| Femoral trochanter | |||||||||
| z-score, mean (SD) | − 0.06 (1.16) |
0.16 (1.02) |
0.13 | − 0.03 (1.30) |
0.05 (0.98) |
0.68 | − 0.10 (0.93) |
0.37 (1.08) |
0.032 |
| Osteopenia, % | 20 | 14 | 0.18 | 23 | 17 | 0.40 | 17 | 7 | 0.13 |
| DXR, metacarpal | |||||||||
| z-score, mean (SD) | 0.01 (1.08) |
− 0.03 (1.13) |
0.80 | − 1.13 (1.23) |
− 0.29 (1.12) |
0.40 | 0.13 (0.91) |
0.45 (1.01) |
0.09 |
| Osteopenia, % | 17 | 20 | 0.34 | 23 | 26 | 0.40 | 12 | 8 | 0.40 |
p values denote differences between groups, and italicized values are significant
DEXA dual-energy X-ray absorptiometry, DXR digital X-ray radiogrammetry