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. 2019 Feb 4;12:31. doi: 10.1186/s12920-019-0476-9

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Mutations in previously reported EAC genes. The presence of SNVs, indels, copy number changes and structural variation in previously reported EAC genes [9, 11, 15, 35]. In the analysis, 74 genes were used. Of these, 24 genes were affected in at least one BE sample and are shown in the oncoplot. a Number of mutations in the 24 genes (b) Recurrent EAC genes that are not fragile sites (c) Mutations in fragile site genes. Sample order for the figure can be found in Additional file 2: Table S1c