Table 1.
Distribution of PrPCWD deposits in lymphoid tissues of clinically affected and non-inoculated white-tailed deer
| Non-inoculated | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Genotype | wt/wt | S96/wt | H95/wt | H95/S96 | wt/wt | |||||||
| D1 | D2 | D3 | D4a | D5 | D6 | D7 | D8 | D9 | D10 | D11 | D12 | |
| Retropharyngeal LN | ++ | +++ | +++ | / | ++ | ++ | ++ | +++ | ++ | +++ | – | – |
| Submandibular LN | +++ | ++ | ++ | / | +++ | ++ | ++ | ++ | / | / | – | – |
| Axillary LN | ++ | ++ | + | / | +++ | ++ | ++ | – | ++ | + | – | – |
| Prescapular LN | + | + | + | / | ++ | + | – | – | + | ++ | – | – |
| Prefemoral LN | ++ | + | ++ | / | + | + | + | – | + | ++ | – | – |
| Popliteal LN | + | + | ++ | / | +++ | + | + | + | + | + | – | – |
| Inguinal LN | + | + | ++ | / | +++ | + | + | – | / | ++ | – | – |
| Tracheobronchial LN | ++ | + | +++ | / | +++ | / | / | / | / | / | – | – |
| Ileocecal LN | / | ++ | ++ | / | +++ | ++ | +++ | ++ | ++ | +++ | – | – |
| Hepatic LN | / | +++ | / | / | / | ++ | ++ | +++ | +++ | +++ | / | / |
| Pancreatic LN | +++ | / | / | / | / | ++ | +++ | / | / | / | – | / |
| Adrenal LN | +++ | ++ | / | / | – | ++ | +++ | ++ | / | ++ | / | – |
| Spleen | + | + | + | + | + | – | + | + | + | + | – | – |
| 3rd eyelid | + | + | ++ | / | -b | - b | - b | + | / | + | – | – |
| Tonsil | +++ | +++ | +++ | +++ | +++ | +++ | +++ | +++ | +++ | +++ | – | – |
| Peyer’s Patches | +++ | +++ | +++ | +++ | +++ | +++ | +++ | / | +++ | +++ | – | – |
| Rectal lymphoid follicles | +++ | +++ | +++ | +++ | ++ | +++ | + | / | / | +++ | – | – |
PrPCWD deposition was detected by IHC
aNo lymph nodes were collected from D4 bNo lymphoid follicles were present in the histological sample. / Sample not available for evaluation