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. 2019 Jan 30;6:161–175. doi: 10.1016/j.toxrep.2019.01.005

Fig. 16.

Fig. 16

(A) The section of subchronic treated male rats lung tissue show air filled alveolar spaces with minimal surrounding interstitial inflammation or congestion of control (distilled water: DW, 10 mL/kg, p.o.) (mild pulmonary inflammatory); HEASR4, HEASR5 and HEASR6 (moderate pulmonary inflammatory) (B) male rats spleen shows lymphoid aggregates which form follicles are seen in control (DW,10 mL/kg, p.o.) (NA); HEASR4, HEASR5 and HEASR6 (surrounding sinuses are packed with red cells, splenic Congestion) (C) section of tissue show mucosal lining and underlying submucosa devoid of inflammatory cell infiltrates with no mucosal ulceration in control (DW, 10 mL/kg, p.o.), HEASR4 and HEASR5 (500 mg/kg) (NA). HEASR6 shows infiltration of mucosa by dense aggregates of inflammatory cells, as well as congestion of submucosal blood vessels (Gastric Inflammation) (D) section of male rats kidney tissue show normocellular glomerular tufts disposed on a background containing renal tubules of control (DW, 10 mL/kg, p.o.) and HEASR4 (NA); HEASR5 (500 mg/kg) and HEASR6 shows congested blood vessels (vascular congestion).