Study IDa	Group in which adverse events were reported	Adverse events reported in intervention group(s)b		Adverse events reported in control groupb
		Adverse events reported	Number in intervention group(s)	Adverse events reported	Number in control group
Gait, balance, and functional training
Almeida 2013	Two intervention groups and control	0, 0	28	0	26
Boongrid 2017	Intervention and control	Knee pain (n = 2)	218	Knee pain (n = 2)	219
Clemson 2012 LiFEc	Intervention only	Pelvic stress fracture (n = 1)	105	‐	106
El‐Khoury 2015	Intervention only	Painful wrist (n = 1), twisted ankle (n = 1), bruises (n = 5), lumbago (n = 1)	352	‐	354
Gschwind 2015	Intervention and control	0	71	0	65
Iliffe 2015 FaME/OEP groupsd	Two intervention groups and control	FaME: 59 (including 'pulled muscles', exacerbation of back/knee pain, muscle/joint soreness) OEP: 69 (including 'pulled muscles', venous problems, exacerbation of back/knee/hip pain and sciatica)	230/227	45 (including exacerbation of back pain)	252
Iwamoto 2009	Intervention and control	0	34	0	33
Liu‐Ambrose 2004 agility groupc	Two intervention groups and control	Agility intervention group: Musculoskeletal complaints (n = 3), shortness of breath (n = 4)	34	Musculoskeletal complaint (n = 1)	32
Nitz 2004	Intervention and control	0	24	0	21
Reinsch 1992	Intervention and control	Pain, bruise, minor injury	129	Pain, bruise, minor injury	101
Sakamoto 2013	Intervention only	Knee pain (n = 2), lower limb pain (n = 1), palpitations (n = 1)	410	‐	455
Sales 2017	Intervention only	Falls during exercise session, no injury (n = 2)	27	‐	21
Siegrist 2016	Intervention and control	0	222	0	156
Skelton 2005	Intervention and control	0	50	0	31
Trombetti 2011	Intervention and control	0	66	0	68
Strength/resistance (including power)
Latham 2003f	Intervention and control	Back and knee pain directly attributable to the exercise programme (n = 18)	112	n = 5 (no further details)	110
Liu‐Ambrose 2004 Resistance groupc	Two intervention groups and control	Resistance intervention group: Musculoskeletal complaints (n = 10)	32	Musculoskeltal complaint (n = 1)4	32
Vogler 2009 Seated groupf	Two intervention groups and control	Musculoskeletal symptoms in all groups: lower back, hip, knee pain			All groups n = 171
3D (Tai Chi)
Li 2005	Intervention and control	0	95	0	93
Wolf 2003	Intervention and control	0	145	0	141
3D (Dance)
Merom 2016	Intervention only	0	275	‐	247
Multiple primary exercise categories
Arkkukangas 2015	Intervention only	0	27	‐	13
Beyer 2007e	Intervention only	Mild and transient pain symptoms: knee (n = 3), hip (n = 1), thigh/gluteal/groin/hamstrings (n = 3), back (n = 2), ankle (n = 1)	24	‐	29
Carter 2002	Intervention and control	0	40	Grade 1 quadriceps strain (n = 1)	40
Clemson 2012 structuredc,e	Intervention only	Groin strain and inguinal hernia surgery (n = 1)	107	‐	106
Haines 2009e,f	Intervention only	Muscle soreness (n = 1)	19	‐	34
Hauer 2001e	Intervention and control	0	31	0	25
Korpelainen 2006	Intervention only	Musculoskeletal problems (n = 3)	84	‐	76
Means 2005e	Intervention only	0	144	‐	94
Ng 2015e	Intervention and control	Joint pain, hip and knee (n = 2); relieved after adjusting training regimen	46	0	46
Rubenstein 2000	Intervention and control	0	28	0	31
Sherrington 2014e,f	Intervention only	Finger pain following grip strength assessment; thigh pain after assessment, low back pain, calf pain, knee pain, exacerbation of hernia symptoms, pre‐existing conditions (mainly musculoskeletal) limited progression of exercises (n = 12)	169	‐	171
Uusi‐Rasi 2015	Intervention and control	Mild musculoskeletal overuse symptoms, pre‐existing osteoarthritic symptoms (n = 25)	91	Mild musculoskeletal overuse symptoms (n = 1)	95
Exercise versus exercise only	Group in which adverse events were reported	Adverse events reported in intervention group		Adverse events reported in intervention group
		Adverse events reported	Number in intervention group	Adverse events reported	Number in intervention group
Ballard 2004	One intervention group	15 weeks ex group: Hip pain (n = 1)	20		19
Barker 2016	One intervention group	Pilates group: Hip pain (n = 1)	20		24
Davis 2011	Two intervention groups and control	1x/week group: Musculoskeletal complaints (n = 14)	52;	2 a week group: Musculoskeletal complaints (n = 5) Balance and tone group: Musculoskeletal complaints (n = 4)	2 a week group = 54; Balance and tone group = 49
Kemmler 2010	Two intervention groups	0	112	0	115
Kwok 2016	Two intervention groups	0	40	0	40
Mirelman 2016	Two intervention groups	Treadmill group: Death from natural causes (n = 1), myocardial infarctions (n = 2), exacerbated orthopaedic‐related pain or arthritis (n = 3), rhabdomyolysis (n = 4). (All deemed not to be caused by the interventions)	136	Virtual reality group: Stroke (n = 1), exacerbated orthopaedic‐related pain or arthritis (n = 4), herpes zoster (n = 1) (All deemed not to be caused by the interventions)	146
Shigematsu 2008	Two intervention groups	0	32	0	36
Yamada 2010	Two intervention groups	Muscle ache and fatigue	29	Muscle ache and fatigue	29
Yamada 2012	Two intervention groups	Muscle ache and fatigue	73	Muscle ache and fatigue	72
Yamada 2013	Two intervention groups	Muscle ache and fatigue	112	Muscle ache and fatigue	118