Comparison 5. Perioperative ketamine versus control: thoracotomy.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
5.1 Opioid consumption at 24 hours	4	241	Mean Difference (IV, Random, 95% CI)	‐5.81 [‐10.28, ‐1.35]
5.2 Opioid consumption at 48 hours	3	191	Mean Difference (IV, Random, 95% CI)	‐12.52 [‐18.34, ‐6.71]
5.3 Pain intensity at rest at 24 hours	13	782	Mean Difference (IV, Random, 95% CI)	‐3.90 [‐8.80, 1.00]
5.4 Pain intensity during movement at 24 hours	5	315	Mean Difference (IV, Random, 95% CI)	‐7.32 [‐20.10, 5.45]
5.5 Pain intensity at rest at 48 hours	9	530	Mean Difference (IV, Random, 95% CI)	‐6.86 [‐10.37, ‐3.35]
5.6 Pain intensity during movement at 48 hours	5	298	Mean Difference (IV, Random, 95% CI)	‐10.64 [‐15.27, ‐6.00]