Fig. 5.

False connections in peritumoral tractogram removed by TIP. a The T1-weighted image shows a glioblastoma located at the right frontoparietal lobe of a 50-year-old patient, whereas the 3D reconstruction illustrates the extent of tumor (flesh-colored) and its surrounding edematous tissue (blue-colored). b Peritumoral tractogram generated from fiber tracking contains possible false connections annotated by red arrows. c TIP automatically removes most of these false connections without manual intervention