Skip to main content
. Author manuscript; available in PMC: 2019 Feb 4.
Published in final edited form as: Expert Rev Anticancer Ther. 2010 Jul;10(7):997–1008. doi: 10.1586/era.10.88

Figure 1. Romidepsin.

Figure 1.

Romidepsin is a bicyclic depsipeptide with a disulfide bond that is converted by cellular reducing activity to yield a free sulfhydryl moiety that is thought to bind to the zinc in the HDAC active site pocket.