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. Author manuscript; available in PMC: 2019 Feb 4.
Published in final edited form as: Biomed Pharmacother. 2004 Jan;58(1):47–55. doi: 10.1016/j.biopha.2003.11.005

Fig. 1.

Fig. 1.

Pathways for the conversion of dietary methionine to cysteine and the intersection of this pathway with folate and one carbon metabolism. The enzymes in each step are as follows: (1) Methionine adenosyl-transferase (MAT); (2) Glycine N-methyltransferase (GNMT); (3) Cystathionine β-synthase (CBS); (4) γ-cystathionine (γ-CYS); (5) Cysteine sulfinic acid decarboxylase (CDO); (6) Betaine homocysteine methyltransferase (BHMT); (7) Methionine synthase (MS); (8) 5,10 methylene tetrahydrofolate dehydrogenase; (9) 5,10 methylene tetrahydrofolate reductase (MTHFR).