Table 2:
S-glutathionylated proteins identified in human diseases.
| Protein | Diseasea | UPR activation |
|---|---|---|
| Actin (85)b | Ischemia/Cardiovascular disease | Yes (86) |
| Friedreich’s ataxia | No | |
| Tau (87) | Alzheimer’s disease | Yes (88) |
| Hemoglobin (89) | Type 2 diabetes | Yes (90) |
| CTFR (81) | Cystic fibrosis | Yes (91) |
| γ-S-crystallin (92) | Cataract disease | Yes (93) |
| Spectrin (57) | Sickle cell anemia | No |
a
Only those diseases in which S-glutathionylated proteins have been identified are shown.
b
Numbers in parentheses indicate cited references.