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. 2019 Jan 28;12(1):dmm036830. doi: 10.1242/dmm.036830

Fig. 5.

Fig. 5.

The cmd1-226 mutant allele, but not wild-type CMD1, restores growth of vps13Δ on YPD+SDS plates. (A) Different CMD1 alleles variously affect the growth of vps13Δ. (B) Wild-type and mutant calmodulin do not influence calcineurin activity in vps13Δ cells. Results were analysed by one-way ANOVA (n=3); P=0.196. Error bars indicate s.d. (C) Effects of calcium addition and CMD1 overexpression on calcineurin activity in wild-type and vps13Δ cells. Results were analysed statistically by two-tailed Student's t-test (n=6; *P<0.05, **P<0.01, ***P<0.001, ****P<0.0001. Error bars indicate s.d. (D) Cmd1-226 does not interact with Myo3-N. Results from a two-hybrid experiment are shown. BD, DNA-binding domain; AD, activating domain.