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. 2019 Jan 28;12(1):dmm036830. doi: 10.1242/dmm.036830

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© 2019. Published by The Company of Biologists Ltd

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

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Fig. 6. — MYO3-N suppresses the actin-cytoskeleton polarisation defect and the canavanine hypersensitivity of vps13 cells. (A) MYO3-N suppresses the actin-cytoskeleton polarisation defect of vps13Δ. Quantification of actin polarisation was analysed using the two-tailed Student's t-test (n=3; cells counted per replicate: 105; 184; 148 for WT [-], 130; 103; 195 for vps13Δ [-], 138; 111; 121 for vps13Δ [MYO3-N]); *P<0.05, ***P<0.001. Error bars indicate s.d. (B) MYO3-N suppresses canavanine hypersensitivity of vps13Δ.