TABLE 3.
Predicted Vaccine Response at Low (10th Percentile) and High (90th Percentile) Mean Bifidobacterium Abundance at 6, 11 and 15 Weeks
| Vaccine Response | 10th Percentilea | 90th Percentilea | Difference, % |
|---|---|---|---|
| BCG SI at 15 wk | 8.63 | 16.0 | 85 |
| TT SI at 15 wk | 7.15 | 12.60 | 76 |
| HBV SI 15 wk | 3.14 | 4.55 | 45 |
| BCG SI at 2 y | 10.0 | 16.4 | 64 |
| TT SI at 2 y | 4.60 | 7.23 | 57 |
| TT plasma IgG 2 y, IU/mL | 33.2 | 47.0 | 42 |
| Stool OPV IgA at 2 y (strain 2, mIU/g protein) | 0.0513 | 0.1060 | 107 |
a
Predicted from regression models described in Methods, holding covariates constant, and by using mean Bifidobacterium abundance at the 10th (abundance = 0.396) and 90th (abundance = 0.814) percentiles.