Table 6.

Multivariate Cox regression analyses for all-cause mortality in patients with moderate AS or AVR in patients with severe AS

	Moderate AS (n=204)		Severe AS (n=102)
	All-cause mortality		AVR
	HR (95% CI)	P value	HR (95% CI)	P value
Rapid early rise in heart rate	16.02 (1.83 to 140.02)	0.012	3.21 (1.70 to 6.08)	<0.001
Age, year	1.13 (1.01 to 1.23)	0.044	1.00 (0.97 to 1.03	0.897
Male sex	8.37 (0.43 to 165.06)	0.162	2.16 (1.08 to 4.29)	0.029
Hypertension	0.11 (0.01 to 2.11)	0.143	0.90 (0.44 to 1.87)	0.781
Doppler stroke volume, mL	1.00 (0.95 to 1.05)	0.990	0.99 (0.98 to 1.01)	0.733
Mean pressure gradient, mm Hg	1.17 (1.00 to 1.36)	0.045	1.03 (1.00 to 1.05)	0.043
Abnormal blood pressure response	0.19 (0.02 to 2.24)	0.185	1.86 (1.00 to 3.44	0.049
Coronary artery disease	14.63 (0.42 to 514.15)	0.140	1.35 (0.74 to 2.47)	0.333

AS, aortic stenosis; AVR, aortic valve replacement.