Table 3.
Endothelial function and Short Form (36) Health (SF-36) survey results, by microvascular function
Variable | Normal microvascular endothelial function (n=199) |
Microvascular endothelial dysfunction (n=258) |
P value |
% change CBF (ACh) | 132.9±80.0 | −12.0±35.7 | <0.001 |
% change CAD (ACh) | −3.8±15.2 | −25.7±20.5 | <0.001 |
% change CAD ≤−20%, n (%) | 32 (16) | 149 (58) | <0.001 |
Coronary flow reserve | 2.93±0.74 | 2.76±0.67 | 0.01 |
Months from study to survey, mean±Standard Deviation | 85.5±55.4 | 82.7±48.2 | 0.27 |
SF-36 Std. Physical component score, mean±SD | 37.0±19.5 | 38.7±17.7 | 0.33 |
SF-36 Std. Mental component score, mean±SD | 40.1±20.1 | 43.9±18.1 | 0.04 |
Physical functioning, age-adjusted and sex-adjusted, mean±SD | 39.5±20.4 | 41.9±18.3 | 0.19 |
Role physical, age-adjusted and sex-adjusted, mean±SD | 37.0±19.4 | 39.2±17.6 | 0.20 |
Body pain, age-adjusted and sex-adjusted, mean±SD | 37.6±18.2 | 39.3±16.7 | 0.28 |
General health, age-adjusted and sex-adjusted, mean±SD | 37.8±19.6 | 40.2±17.7 | 0.16 |
Vitality, age-adjusted and sex-adjusted, mean±SD | 36.0±17.9 | 39.1±17.0 | 0.05 |
Social function, age-adjusted and sex-adjusted, mean±SD | 39.3±20 | 42.2±18.3 | 0.11 |
Role emotional, age-adjusted and sex-adjusted, mean±SD | 40.4±20.0 | 43.6±18.5 | 0.07 |
Mental health, age-adjusted and sex-adjusted, mean±SD | 40.7±20.0 | 44.2±17.7 | 0.04 |
ACh, acetylcholine; CAD, coronary artery disease.