Table 2.
Comparison of C3 and C3/C2 levels between race/ethnic groups, and stratified by gender, gestational age and birth weight.
| Asian | Black | Hispanic | White | |
|---|---|---|---|---|
| Difference in C3 levels between race/ethnic groupsa | ||||
| Asian | – | 0.39(0.30 to 0.49, P < .001) | − 0.13(−0.19 to 0.07, P=.19) | − 0.03(−0.10 to 0.03, P=.09) |
| Black | – | – | −0.52(−0.61 to −0.44, P < .001) | −0.43(−0.51 to −0.34, P < .001) |
| Hispanic | – | – | – | 0.10(0.05 to 0.14, P < .001) |
| White | – | – | – | – |
| Difference of C3/C2 levels between race/ethnic groupsa | ||||
| Asian | – | 0.71(0.62 to 0.81, P < .001) | −0.16(−0.22 to −0.10, P < .001) | 0.08(0.01 to 0.14, P=.20) |
| Black | – | – | −0.86(−0.94 to −0.78, P < .001) | −0.64(−0.73 to −0.55, P < .001) |
| Hispanic | – | – | – | 0.23(0.19 to 0.28, P < .001) |
| White | – | – | – | – |
| Difference in analyte levels between male and female within each race/ethnic groupb | ||||
| C3 | 0.15(0.04 to 0.25, P=.006) | −0.01(−0.16 to 0.14, P=.85) | 0.08(0.03 to 0.14, P=.004) | 0.09(0.01 to 0.16, P=.03) |
| C3/C2 | −0.07(−0.17 to 0.04, P=.21) | −0.32(−0.47 to −0.17, P < .001) | −0.18(−0.24 to −0.13, P < .001) | −0.21(−0.29 to −0.14, P < .001) |
| Difference in analyte levels between preterm and term infants within each race/ethnic groupc | ||||
| C3 | 0.64(0.40 to 0.88, P < .001) | −0.11(−0.39 to 0.17, P=.43) | 0.37(0.25 to 0.49, P < .001) | 0.40(0.23 to 0.57, P < .001) |
| C3/C2 | 0.34(0.11 to 0.58, P < .001) | 0.14(−0.14 to 0.42, P=.28) | 0.44(0.32 to 0.56, P < .001) | 0.35(0.18 to 0.51, P=.002) |
| Difference in analyte levels between infants with higher and lower BW born at GA of 39 weeksd | ||||
| C3 (f) | 0.25(−0.05 to 0.56, P=.096) | 0.53(0.06 to 1.01, P=.026) | 0.56(0.39 to 0.73, P < .001) | 0.36(0.13 to 0.59, P=.002) |
| C3 (m) | 0.26(−0.02 to 0.54, P=.066) | 0.40(−0.06 to 0.85, P=.082) | 0.22(0.06 to 0.39, P=.008) | 0.42(0.19 to 0.65, P < .001) |
| C3/C2 (f) | 0.41(0.11 to 0.71, P=.008) | 0.75(0.26 to 1.23, P=.002) | 0.53(0.36 to 0.70, P < .001) | 0.47(0.24 to 0.71, P < .001) |
| C3/C2 (m) | 0.55(0.26 to 0.83, P < .001) | 0.39(−0.06 to 0.85, P=.087) | 0.28(0.11 to 0.44, P=.001) | 0.38(0.16 to 0.61, P < .001) |
Pairwise comparison of groups was performed using Cohen's d with the 95% CI and P value of each t-test in parenthesis.
a
Positive Cohen's d indicates higher C3 or C3/C2 values in row group than in column group.
b
Positive Cohen's d indicates higher C3 or C3/C2 values in males than in females.
c
Positive Cohen's d indicates higher C3 or C3/C2 values in preterm than in full-term infants.
d
Positive Cohen's d indicates higher C3 or C3/C2 values in newborns in the highest BW tertile than newborns in the lowest BW tertile (Abbreviations: f=female, m=male).