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. Author manuscript; available in PMC: 2019 Feb 4.
Published in final edited form as: FEBS J. 2017 Sep 30;284(21):3662–3683. doi: 10.1111/febs.14263

Fig. 3.

Fig. 3.

Kinetic characterization of DNA Cleavage by p1-Cu and p3-Cu. (A) Electrophoretic monitoring of piscidin-induced cleavage of pUC19 showing loss of supercoiled (S) plasmid with corresponding increase in the nicked (N) and linearized (L) form. (B) Pseudo first-order integrated rate law plots of in vitro DNA cleavage promoted by the piscidins. Blank runs represent experiments with H2O2 and ascorbic acid but without any metallopeptide. Data represent mean ± SEM (n = 3).