Figure 3.

Antitumor effects of anti‐l‐type amino acid transporter 1 (anti‐LAT1) mAb in the established tumor model. Six days after LS‐174T human colon cancer cells (5 × 10⁶) were s.c. inoculated into athymic mice, visible tumors were confirmed in all mice. At this point (day 0), anti‐LAT1 mAb (Ab1) or isotype control IgG mAb (100 μg) was i.p. injected, followed by two additional injections of the same amount of mAb on day 8 and day 15. Data were expressed as mean ± SEM, and statistical analysis was done using two‐way analysis of variance