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. Author manuscript; available in PMC: 2019 Feb 4.
Published in final edited form as: Small. 2018 Nov 9;14(50):e1803601. doi: 10.1002/smll.201803601

Figure 7.

Figure 7.

Anti-cancer efficacy of PTX@QA-NP and Taxol in female nude mice with MDA-MB-231 xenografts. (a) Treatments given as a single dose equivalent to PTX 20 mg/kg. Mice were sacrificed once the tumor volume (V) reached 2000 mm3 or showed any signs of morbidity defined in the animal protocol. n=5 mice per group. Tumor specific growth rate is defined as ΔlogV/Δt (t: time in days). *: p<0.05 by unpaired t-test. (b) Treatments given as five doses of 20 mg PTX equivalent/kg/dose over 2 weeks. n=5 mice per group. *: p<0.05 by Gehan-Breslow-Wilcoxon test. Inset graphs show the tumor growth and survival over 150 days.