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| PK Parameter | Formulation | |
|---|---|---|
| PTX@PEG-NP | PTX@QA-NP | |
| t1/2 (h) | 7.7 | 5.4 |
| Cmax (μg/mL) | 3.4 (0.5) | 2.4 (0.05) |
| AUC0-last (h•μg/mL) | 10.6 (0.4) | 11.0 (0.1) |
| AUC0-∞ (h•μg/mL) | 11.3 | 11.6 |
| MRT (h) | 5.8 | 6.3 |
| CL (L/h/kg) | 1.8 | 1.7 |
| Vss (L/kg) | 10.4 | 11.0 |
PK parameters were obtained from non-compartmental analyses. The numbers in parentheses denote the standard errors (SE) associated with estimated parameters.
