Table 1:
Participant Characteristics
| Baseline (n=93) |
6-weeks (n=83) |
1-year (n=72) |
P-value Baseline vs. 1-year |
|
|---|---|---|---|---|
| Age (years) | 14.4±1.6 | 14.8±1.6 | 15.5±3.4 | <0.01 |
| Race, n (%) | - | |||
| Black | 58 (62%) | 51 (61%) | 45 (63%) | |
| White | 15 (18%) | 13 (16%) | 11 (15%) | |
| Asian | 3 (3%) | 3 (4%) | 3 (4%) | |
| Mixed race | 17 (18%) | 16 (19%) | 13 (18%) | |
| BMI (kg/m2) | 32.6±6.5 | - | 33.9±9.9 | 0.31 |
| Systolic BP (mmHg)* | 118.5±9.5 | - | - | - |
| Diastolic BP (mmHg)* | 64.6±8.3 | - | - | - |
| Fasting glucose (mg/dL) | 89.0±7.5 | 88.6±7.7 | 88.2±7.1 | 0.52 |
| 2-hr glucose (mg/dL) | 103.3±21.4 | 104.6±20.5 | 107.1±22.6 | 0.26 |
| Fasting insulin (μU/mL)# | 20.3 (13.8–27.7) | 20.5 (15.2–27.9) | 18.8 (12.9–33.8) | 0.85 |
| Pre-diabetes, n (%) | 12 (13) | 12 (14) | 7 (13) | 0.53 |
| HbA1c (%) | 5.3±0.4 | 5.3±0.4 | 5.4±0.4 | 0.03 |
| Insulinogenic index | 4.2 (2.5–6.6) | 4.1 (2.9–6.9) | 3.6 (2.1–6.2) | 0.77 |
| Matsuda index | 2.3 (1.5–3.2) | 2.2 (1.4–3.0) | 2.7 (1.3–4.0) | 0.99 |
Data are mean±SD, n (%) or median (25th-75th percentile). Paired t-tests and Fisher exact tests were used to compare characteristics at baseline to 1-year. BMI: body mass index; HbA1c: glycosylated hemoglobin A1c. (*n=81, #n=91)