Table 2:

Diagnostic accuracy and reproducibility of OGTT features for prediabetes.

	Baseline (n=83)			6-weeks (n=83)			Reproducibility
OGTT Feature	Sensitivity	Specificity	ROC-AUC (95% CI)	Sensitivity	Specificity	ROC-AUC (95% CI)	Kappa	95% CI
Morphological features
Glucose peak >30 mins	0.70	0.71	0.71 (0.55 – 0.86)	0.58	0.62	0.60 (0.45 – 0.76)	0.23	0.02–0.44
Monophasic curve	0.60	0.53	0.57 (0.40 – 0.74)	0.58	0.48	0.53 (0.37 – 0.69)	0.23	0.02–0.43
1-hr glucose≥155mg/dL	0.40	0.95	0.67 (0.51 – 0.83)	0.33	0.98	0.66 (0.52 – 0.79)	0.42	0.07–0.77
COMBO	0.66	0.75	0.71 (0.56–0.85)	0.41	0.73	0.57 (0.42–0.72)	0.46	0.30–0.61
Gold-standard criteria
Fasting glucose ≥100 mg/dL							0.38	0.04–0.72
2-hr glucose ≥140 mg/dL							0.28	−0.08–0.64

OGTT: oral glucose tolerance test; COMBO: glucose peak>30mins and/or 1-hr glucose ≥155mg/dL.