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. Author manuscript; available in PMC: 2020 Feb 4.
Published in final edited form as: Chem Soc Rev. 2019 Feb 4;48(3):771–813. doi: 10.1039/c8cs00304a

Fig. 3.

Fig. 3

Quinone-based bioreductive compounds and proposed activation mechanism for MMC (1) and porfiromycin (2). As shown schematically, this activation results in the formation of a DNA alkylating agent.