Figure 1:

The lower limb musculoskeletal finite element model with two calibrated specimen specific knees (M1 pictured). The knees included TF and PF soft tissue structures whose response was calibrated to in vitro experiments (Ali et al., 2016; Harris et al., 2016). The model includes 15 unique muscles comprised of 20 musculotendon fibers which span the lower limb previously calibrated to match mean healthy isometric knee flexion-extension torque results (Hume et al., 2018).