Table 2.
Class | Examples | Structure | Mechanism |
---|---|---|---|
Suicide inhibitors | methoxy arachidonyl fluorophosphonate (MAFP) | covalent binding to catalytic serine | |
isopropyl dodecylfluorophosphonate (IDFP) | |||
cationic amphiphiles | amiodarone | inhibition of electrostatic charge interaction between cationic residues and anionic phospholipids | |
D-threo-1-phenyl-2-decanoylamino-3-morpholino-1-propanol (PDMP) |