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. Author manuscript; available in PMC: 2020 Jun 1.
Published in final edited form as: Biochim Biophys Acta Mol Cell Biol Lipids. 2018 Aug 2;1864(6):932–940. doi: 10.1016/j.bbalip.2018.07.012

Table 2.

Inhibitors of PLA2G15.

Class Examples Structure Mechanism

Suicide inhibitors methoxy arachidonyl fluorophosphonate (MAFP) graphic file with name nihms-1503190-t0006.jpg covalent binding to catalytic serine
isopropyl dodecylfluorophosphonate (IDFP)

cationic amphiphiles amiodarone graphic file with name nihms-1503190-t0007.jpg inhibition of electrostatic charge interaction between cationic residues and anionic phospholipids
D-threo-1-phenyl-2-decanoylamino-3-morpholino-1-propanol (PDMP)