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. 2019 Feb 5;39(2):BSR20180480. doi: 10.1042/BSR20180480

Figure 4. Rab7a overexpression reduces the apoptosis and promotes the proliferation and growth of MCF-7 cells.

Figure 4

(A) Green fluorescence images of Rab7a overexpressed (OE) and Ctrl (NC) MCF-7 cells. (B) Western blots of Rab7a in cells as shown in (A). (C) Cell viability of Rab7a OE and Ctrl (NC) MCF-7 cells was determined by MTT assay from day 1 to 5. **P<0.01; n=5. (D) Colony formation of indicated cells. (E) Quantitative results of colony formation in (D). **P<0.01; n=3. (F,G) Flow cytometry analysis of apoptosis revealed that Rab7a overexpression suppressed MCF-7 cell apoptosis. *P<0.05; n=3.