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. 2019 Feb 5;39(2):BSR20180480. doi: 10.1042/BSR20180480

Figure 7. Rab7a silencing causes dysregulation of numerous genes in MDA-MB-231 cells.

Figure 7

(A) Heat map of 634 genes (262 genes up-regulated and 372 genes down-regulated) in MDA-MB-231 cells infected with lentivirus expressing shNC and shRab7a (criteria P<0.05, fold-change > 1.5). (B) Functional pathway enrichment of dysregulated genes was analyzed by IPA software. (C) The expression of eIF4E, PRKAA1, and RPS6KB1 in shNC and shRab7a MDA-MB-231 cells was determined by Western blot assay. GAPDH serves as the internal control.