Table 2.
SSNS studies implicating MHC II loci.
| Study population | Cohort size (n) | Gene | References |
|---|---|---|---|
| UK Caucasian | 40 | HLA-DR7 | (75) |
| HLA-DQW2 | |||
| U.S. Caucasian | 32 | HLA-DQW2 | (76) |
| French and German | 161 | HLA-DQB | (24) |
| HLA-DQA | |||
| Japanese | 24 | HLA-DQB1 | (25) |
| Japanese | 30 | HLA-DQA1 | (77) |
| HLA-DQB1 | |||
| Chinese (Taiwan) | 59 | HLA-DQB1 | (78) |
| HLA-DR | |||
| French | 75 | HLA-DQA1 | (79) |
| Dutch | 146 | ||
| British | 335 | ||
| South Indian | 76 | HLA DRB1 | (23) |
| HLA DQB1 | |||
| South Asian | 214 | HLA-DQA1 | (22) |
| U.S. white | 100 | ||
| European | 323 | HLA-DQA1 | (80) |
| African American | 65 | HLA-DQA1 | (26) |
| European, North African, Southeast Asian | 131 | HLA-DQA1 | (59) |
| Japanese | 224 | HLA-DR | (28) |
| Japanese | 216 | HLA-DQ | |
| French caucasian | 132 | HLA-DR | (27) |
| European caucasian | 133 | HLA-DQ | |
| African | 56 | ||
| Maghrebian | 85 |