Skip to main content
. 2019 Jan 29;10:3. doi: 10.3389/fgene.2019.00003

Figure 1.

Figure 1

PmiRGO flowchart. It consists of six steps: (A) three networks (miRNA co-expression network, miRNA-target interaction network, and PPI network) were constructed according to the co-expression profiles, miRNA-target gene interactions, and protein-protein interactions, respectively. (B) By mapping the target genes into PPI network, the three networks were integrated to build a global heterogeneous network. (C) DeepWalk was employed to learn the latent representations of the network as features of the global heterogeneous network. (D) For each miRNA or protein, a feature vector was obtained. (E) SVM models were trained and the miRNA2GO-337 dataset were used to evaluate the performance. (F) The GO annotations of each miRNA in the miRNA2GO-337 dataset were predicted.